The lean, scrappy playbook to launch a DTC compounded GLP-1 telehealth brand. No $50K startup cost. No live consults. Just an async intake form, a prescriber API, and a compounding pharmacy.
Hims, Ro, Found, Henry Meds — none of them do live video consults for most patients. The patient fills out a medical intake form. A prescriber reviews it async in 2-5 minutes. If they qualify, the rx goes to the pharmacy and medication ships. No appointments. No scheduling. No video calls.
Why this is superior: Prescriber can review 50-100+ patients/day. No scheduling headaches. Patient gets faster service. Your per-consult cost drops to $8-25 instead of $30-75.
| Patient pays | $249-349/month (subscription) |
| Compounding pharmacy cost | ~$40-80/vial |
| Prescriber async review | ~$8-25/consult |
| Shipping | ~$5-10/shipment |
| Gross margin per patient | $100-250/month |
| Avg patient lifetime | 4-8 months |
| LTV per patient | $400-2,000 |
This is the #1 bottleneck. 4-8 weeks to approve. Every day you delay = a day longer before you can run real ads. Knock this out TODAY.
LegitScript reviews your website extensively. It must have ALL of these before you apply:
| LLC (Wyoming) | $100 |
| LegitScript application | $1,000 |
| First month ads | $500-1,000 |
| Domain + tools | ~$50 |
| TOTAL | $1,650-2,150 |
| Everything else is per-patient cost — you only spend when you earn | |
Since you're building the platform yourself, you just need prescribers via API. You don't need a full turnkey solution.
You have a warm LinkedIn lead (Joshua). API-based telehealth prescribing + pharmacy fulfillment. Raised $6M. Their API: send patient data → prescriber assigned → rx sent to pharmacy. White-label, HIPAA compliant.
Cost: $0 base, per-consult pricing. Coverage: 50 states. Async: Yes.
Founded by Dr. Marc Serota (licensed in 45 states, quad board-certified including obesity medicine). Physician-ONLY network — no NPs, higher credibility. Simple API: patient fills intake → docs review async → rx sent. Telehealth business consulting included.
Cost: Per-consult. Coverage: 45 states. Async: Yes.
Powers Fridays (major GLP-1 brand) and MEDVi (100,000+ patients). 50-state clinician bench. Scale-ready. They handle all clinician management, licensing, compliance.
Cost: $20-75/consult. Coverage: 50 states. Async: Yes.
Post on Indeed/LinkedIn for "Contract Weight Loss Prescriber — Telehealth." Tons of NPs looking for remote 1099 gigs. $8-25/async consult. Start with NP independent practice states (21 states: AZ, CO, CT, HI, ID, IA, ME, MD, MN, MT, NE, NV, NH, NM, ND, OR, RI, SD, VT, WA, WY).
Cost: $8-25/consult. Best margins but more work to manage.
Compounded semaglutide: FDA removed from shortage list but legal challenges ongoing. Most DTC brands still offering through compliant 503A/503B pharmacies. Some compounders using modified formulations to maintain legality.
Compounded tirzepatide: FDA ended compounding discretion. Effectively dead for broad DTC.
Bottom line: Compounded semaglutide still viable with the right pharmacy partner. They carry the compounding liability, not your platform. Choose a pharmacy with strong legal counsel.
This IS your product. Patient fills this out, prescriber reviews it async, done. Mobile-first, one question per screen, progress bar. Build on Lovable.
Cost: $1,000 application + $1,000/year
Timeline: 4-8 weeks for approval
Why: Meta and Google require it for ads promoting telehealth with prescription medications. Without it, you're limited to generic "weight loss program" messaging. With it, you unlock the real ad inventory.
Apply ASAP. Run generic ads while you wait. The moment it's approved, you scale.
MSO + PC Model: Your company (MSO) handles tech, marketing, operations. A physician-owned Professional Corporation (PC) handles clinical decisions. This is how Hims, Ro, and every DTC telehealth company structures for legal protection.
For now, your LLC + prescriber API partner handles the clinical side. Formalize the MSO/PC structure when you're making real money.
Budget: $20-50/day
Angle: "Doctor-guided weight loss programs" — no drug names, no prescription mentions
Target: US, 25-55, interests: weight loss, health, wellness, fitness
Hooks that work:
Full prescription medication advertising unlocked. Can mention GLP-1 treatment category (still no brand names for compounded). Much broader ad inventory, lower CPM, higher intent.
| Metric | Conservative | Optimistic |
|---|---|---|
| Patient price/mo | $249 | $349 |
| Pharmacy cost | $80 | $40 |
| Prescriber cost | $25 | $10 |
| Shipping | $10 | $5 |
| Gross margin/patient/mo | $134 | $294 |
| CAC (Meta ads) | $150 | $50 |
| Avg lifetime (months) | 4 | 8 |
| LTV | $536 | $2,352 |
| LTV:CAC | 3.6:1 | 47:1 |
| Patients | Monthly Revenue | Monthly Profit (est) |
|---|---|---|
| 50 | $12,500-17,500 | $5,000-12,500 |
| 200 | $50,000-70,000 | $20,000-50,000 |
| 500 | $125,000-175,000 | $50,000-125,000 |
| 1,000 | $250,000-350,000 | $100,000-250,000 |
| 4,000 | $1,000,000+ | $400,000-1,000,000 |
| Company | Model | Pricing | Weakness |
|---|---|---|---|
| Hims & Hers | Brand + compounded | $199-349/mo | FDA forced them to pull $49 pill. Huge overhead. |
| Ro | Brand-focused | $145-499/mo | Expensive, insurance-dependent |
| Found | Compounded + brand | $129-249/mo | Lower prices = lower margins |
| Noom | Program + meds | $149-299/mo | Coaching-heavy, complex model |
| Henry Meds | Compounded | $199-349/mo | Generic brand, no differentiation |
| Fridays | Compounded (OpenLoop) | $149-299/mo | New, unproven at scale |
| Calibrate | Premium program | $1,500+ upfront | Expensive, small market |
| Sesame | Marketplace | Varies | Not DTC-focused |
Time to cook. 🔥
Built by Ron — Feb 19, 2026